Tsp 1 antibody

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August undefined, 2024

WebThrombospondin-1 (TSP-1) is a 150‑180 kDa charter member of the thrombospondin family of extracellular matrix proteins. Human TSP‑1 is synthesized as an 1170 amino acid (aa) precursor that contains an 18 aa signal sequence and 1152 aa mature molecule. The mature molecule has been described as containing three distinct regions that create ... WebThe function of the type II repeats in unclear. TSP‑1 is secreted as a disulfide-linked 450 kDa homotrimer. The cysteines responsible lie just N‑terminal to the first type I TSP repeat. …

Thrombospondin 1 Monoclonal Antibody (D4.6) - Thermo Fisher …

WebHere we characterize a novel TSP-1 interaction with T. cruzi that enhances cellular infection. We show that labeled TSP-1 interacts specifically with the surface of T. cruzi trypomastigotes. We used TSP-1 to pull down interacting parasite surface proteins that were identified by mass spectrometry. WebThe Human TSP-1 solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the … fonagy et al 1991

Anti-Thrombospondin 1 Antibodies Invitrogen - Thermo …

Web(ab85762) Anti-Thrombospondin 1 antibody Supplier Abcam. Host Rabbit Type Primary Clonality Polyclonal Conjugate Unconjugated Target Thrombospondin-1 (Human) UniProt P07996 - TSP1_HUMAN. Gene ... THBS1, TSP, TSP1, TSP-1, THBS, THBS-1. View additional product information. Experiments from the literature. Loading published images for this … WebNational Center for Biotechnology Information WebAnti-TSP-1 Antibody Products. TSP-1 is an alias for the human gene, Protease, serine 55, or, PRSS55. Other names include: Serine protease 55; T-SP1; Serine protease 55 ; CT153; … laura olsen books

(ab85762) Anti-Thrombospondin 1 antibody - Abcam - CiteAb

WebAll lanes : Anti-Thrombospondin 1 antibody [EPR22927-54] (ab267388) at 1/1000 dilution Lane 1 : HUVEC (human umbilical vein endothelial cell) whole cell lysate Lane 2 : Mouse … font amigosWebMouse monoclonal Thrombospondin 1 antibody [A6.1]. ... TSP-1 axis. Diabetes Res Clin Pract 165:108140 (2024). PubMed: 32277954; View all Publications for this product. … laura padden spokane valley

"WebApr 9, 2024 · The perception of human T-cell leukemia virus type 1 (HTlV-1) infection as a “silent disease” has recently given way to concern that its presence may be having a variety of effects. HTLV-1 is known to cause adult T-cell leukemia (ATL), an aggressive cancer of peripheral CD4 T cells; however, it is also responsible for HTLV-1-associated … " - Tsp 1 antibody

Tsp 1 antibody

Thrombospondin-1 interacts with Trypanosoma cruzi surface …

WebMay 10, 2010 · Neutralizing TSP-1 antibody (clone A4.1; Thermo Fisher, Fremont, CA, USA) was used at 40 μg/ml as previously described. 5 Controls for the neutralizing activity of this antibody were included in ... WebGet better batch-to-batch reproducibility with a recombinant antibody. Anti-Thrombospondin 1 antibody [EPR22927-54] (ab267388) Research with confidence – consistent and reproducible results with every batch. Long-term and scalable supply – powered by recombinant technology for fast production. Success from the first experiment – …

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WebPolyclonal Antibody for studying Thrombospondin-1. Cited in 6 publications. Validated for Western Blotting. Highly specific and rigorously validated in-house, Thrombospondin-1 … WebBackground: Thrombospondin-1 (TSP-1) has been implicated in many different processes based in part on inhibitory activities of anti-TSP-1 monoclonal antibodies (mAbs). …

WebFlow cytometry analysis of Thrombospondin in HepG2 cells compared to an isotype control (blue). Cells were harvested, adjusted to a concentration of 1-5x10^6 cells/mL, fixed with … WebThe cells were labeled with Thrombospondin 1 (A4.1) Mouse Monoclonal Antibody (Product # MA5-13377) at 2 µg/mL in 0.1% BSA and incubated for 3 hours at room temperature and then labeled with ... are presented as mean +- SD. ( c ) Angiogenic activity ( d ) and VEGF levels were evaluated in PrEC as above. ( e ) TSP-1 expression was evaluated by ...

WebThrombospondin-1 (UniProt P07996; also known as THBS-1, TSP-1) is encoded by the THBS1 (also known as THBS, TSP, TSP1) gene (Gene ID 7057) in human. Thrombospondin-1 (TSP-1) is a member of the TSP family of calcium-binding extracellular matrix proteins. The TSP family consists of the homotrimeric TSP-1 and TSP-2, as well as the … WebHuman T lymphotropic virus type 1-assoicated (HTLV-1-associated) myelopathy/tropical spastic paraparesis (HAM/TSP) is a neuroinflammatory disease caused by the persistent proliferation of HTLV-1 ...

WebLyophilized or Liquid. Concentration. - 100 μg (in 100 μl): 1 mg/ml. Storage. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at …

WebThrombospondin-1 (TSP-1) is a secreted homotrimeric protein that regulates a wide range of cellular functions including their interactions with other cells and with the extracellular matrix (ECM). TSP-1 counteracts the angiogenic, hypotensive, and anti-thrombotic effects of nitric oxide (NO). It binds and neutralizes VEGF, blocks VEGF R2 ... fondos azules pngWebA purified peptide of the CD47-binding TSP-1 C-terminal domain (E3T3C1) or functional blocking antibodies to TSP-1 (α-TSP-1 C-terminus) or CD47 (α-CD47) were incubated with MVs for 48 hours. Effects of antibody treatment of knockout-derived MVs were not determined (n.d.). laura ottmanWebNov 11, 2024 · The recombinant TSP-1 protein promoted proliferation, survival, and migration of CTCL cell lines, and anti-CD47 or anti-TSP-1 neutralizing antibody inhibited … fono bus teléfono jesús maríaWebThe cells were labeled with Thrombospondin 1 (D4.6) Mouse Monoclonal Antibody (Product # MA5-13385) at 2 µg/mL in 0.1% BSA and incubated for 3 hours at room temperature and … font jametWebThe cells were labeled with Thrombospondin 1 (A4.1) Mouse Monoclonal Antibody (Product # MA5-13377) at 2 µg/mL in 0.1% BSA and incubated for 3 hours at room temperature and … laura pakkiWebAug 1, 2002 · The anti-TSP-1 blocking antibody strongly inhibited platelet-induced SMC proliferation by approximately 60%. Analysis of the receptors for TSP-1 accumulation on the SMC surface revealed that beta1 integrins are mainly involved. The anti-beta1 integrin blocking antibody, ... laura pekieneWebJun 20, 2024 · We investigated the role that thrombospondin-1 (TSP-1) ... We investigated whether antibody production to antigens arising in the subarachnoid space is depressed acutely after spinal cord injury ... font kodakku