WebA high RDW may be the only indication of simultaneous microcytic and macrocytic … WebApr 13, 2024 · Extremely high MCV (>130 fL) narrows the differential diagnosis, to include ART treatment for HIV infection, use of hydroxyurea, and vitamin B12 or folate deficiency. 32 The MCV values may be falsely elevated when significant reticulocytosis is present, because the reticulocyte volume is high. 33 Moreover, hyperglycemia, marked leukocytosis, and …
DISCUSSION: high MCH with normal B12 and folate
WebThe MCV is often greater than 110 and an MCV >120 is almost pathognomonic for megaloblastic anemia. Hyperchromic macro-ovalocytes are relatively specific but insensitive for the diagnosis. On physical exam, look for an atrophic tongue. Causes include: B12 deficiency: check serum B12 level. WebIf the RDW is normal and the MCV is high, the RBCs are likely all macrocytic If the MCV and RDW are both normal, the RBCs are likely all about the same normal size MCV = normal ... • Elevated methylmalonic acid (MMA) +/- elevated homocysteine •Folate: neural tube defects (in pregnant women), early cardiovascular disease, malignancy ... gyft sweater
Three neglected numbers in the CBC: The RDW, MPV, and NRBC …
WebFeb 1, 2024 · First-trimester folate-cobalamin status interactions were associated with plasma MMA and MCV throughout pregnancy and were not associated with the other investigated outcomes. Background Periconception folic acid supplementation is widespread, but how it interacts with cobalamin status is rarely considered. Objective The … WebMar 31, 2024 · High intakes of folic acid may mask a vitamin B12 deficiency. In turn, this … WebMay 25, 2024 · You may have high MCH if you have very low vitamin B12 or folate. These are B vitamins that help you make red blood cells. This may happen if: Your stomach can’t absorb vitamin B12 ( pernicious anemia) … gyft support