WebNov 14, 2024 · Background Acyclovir is one of the most common prescribed antiviral drugs. Acyclovir nephrotoxicity occurs in approximately 12–48% of cases. It can present in clinical practice as acute kidney injury (AKI), crystal-induced nephropathy, acute tubulointerstitial nephritis, and rarely, as tubular dysfunction. Electrolytes abnormalities like hypokalemia, … WebOct 25, 2013 · The molecular mechanisms of crystal-induced inflammation involve crystal uptake into intracellular lysosomes and eventually lysosomal leakage, …
Acute Methotrexate-Induced Crystal Nephropathy NEJM
WebAug 1, 2024 · The mechanism of nephrotoxicity most often described in aciclovir therapy is crystal nephropathy. Aciclovir has low urine solubility and may precipitate or crystallize in tubular lumens causing tubular obstruction, 114 particularly in the setting of low urine output. Use of high doses or administration via rapid intravenous bolus may further ... WebNov 1, 2024 · Abstract. Crystal-induced acute kidney injury (AKI) is caused by the intratubular precipitation of crystals, which results in obstruction and kidney injury. Levofloxacin is commonly used ... pont elisabeth budapest
Chronic Kidney Disease in the United States, 2024 - CDC
WebTypes of Medical Malpractice That Can Lead to Kidney Damage. Failure to diagnose When a physician fails to diagnose kidney disease, or a condition that could lead to … WebNov 2, 2009 · Crystal-induced kidney disease refers to kidney injury caused by intratubular crystal deposition of calcium salts, medications, or other chemicals. The major risk factors for crystal deposition include hypercalcemia and/or hypercalciuria, hyperoxalosis and/or hyperoxaluria, and increased serum and/or urinary phosphate levels. The risk of crystal … WebJul 21, 2024 · IgA nephropathy is often detected after you notice blood in your urine or when a routine test shows that you have protein or blood in your urine. These tests can … shaonan halal grocery store